Stephan Schaller is a systems scientist passionate about Model-Based Drug Discovery, Development, and Dosing (MI4D) with over 13 years of industry experience. His experience ranges from target validation in the early phases of drug discovery, to drug toxicity and efficacy evaluations, to the development of automated decision support systems for drug dosing at the point of care. Stephan Schaller founded esqLABS GmbH in 2017 to advance the integration of computational methods in healthcare to derive effective computational platforms for drug-, device- and treatment development and -optimization (personalization). During his time in the industry, he has leveraged physiologically based concepts for decision-making support to drug discovery, research, and development teams in various therapeutic areas, including oncology, immunology, hematology, cardiovascular, and metabolic disease. Stephan Schaller is the chair of the board of Open-Systems-Pharmacology.com, a consortium to develop the open-source tools PK-Sim® and MoBi® user across the pharmaceutical (healthcare), chemical and crop industry for the analysis of in vitro, animal in vivo and human in vivo data to provide insights to research and development teams on the mode-of-action of the toxicity/safety and the (clinical) efficacy of drug therapies and chemicals.

Stephan Schaller studied control systems engineering and systems biology at the University of Stuttgart, Germany and received his doctoral degree in control systems engineering and systems biology and received his doctoral degree in computational engineering from the RWTH Aachen University-Germany in collaboration with Bayer for the development of an automated decision support system for insulin dosing in type 1 diabetes patients.

Positions and Scientific Appointments

2017 – Present Managing Director, esqLABS GmbH, Saterland, Germany

2021 – Present Chair, Open Systems Pharmacology Management Team, Germany

2021 – Present Adjunct Faculty, Department of Pharmacology, University of Florida, St. Louis, MO

2015 – 2017 Senior Scientist, Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany

2013 – 2015 Scientist, Bayer Technology Services, Leverkusen, Germany

2010 – 2014 PhD Scholarship, Bayer Technology Services, Leverkusen, Germany and RWTH Aachen University, Aachen, Germany

2009 – 2010 Research Engineer, Insilico Biotechnology AG, Stuttgart, Germany

2022 – Present Member, Society of Toxicology (SOT)

2014 – Present Member, American Society of Clinical Pharmacology and Therapeutics (ASCPT)

2014 – Present Member, International Society of Pharmacometrics (ISoP)